With this Master's Degree, you will know in depth the advances in microbiota, and the clinical use of probiotics and prebiotics in multiple pathologies"

The Human Microbiota undergoes changes as a consequence of the influence of multiple factors, including diet, lifestyle or pharmacological treatments, which generate alterations in this bacterial ecosystem. This abnormal interaction that the organism could have with it is related to certain processes: allergic, acute and chronic intestinal diseases, obesity and metabolic syndrome, neurological diseases, dermatitis and other alterations in the dermis and even some types of cancer. It is, therefore, common that behind certain ailments or pathologies there is an imbalance in the balance of the Human Microbiota. 

Large laboratories and research centers have promoted lines of research in this field, as well as the creation of increasingly effective and precise probiotics and prebiotics applied for the prevention and treatment of certain pathologies. A peak moment in the study and advancement of the Human Microbiota, to which the physiotherapy professional cannot be alien. 

That is why TTECH Global University has designed this Master's Degree, where the professionals will be able to obtain the necessary actualization from the hand of a specialized teaching team with extensive experience in this area. Thus, through a theoretical and practical approach, students will delve into the microbiome and metagenomics, advances in the clinical application of probiotics and prebiotics in urology, gynecology and immunology. 
In addition, this university program has clinical case studies and videos in detail that will favor a much more direct and close update by the physiotherapist. Essential readings, interactive summaries and video summaries complement this intensive syllabus. 

This is an excellent opportunity for professionals to access a flexible, online university program that is compatible with the most demanding responsibilities. In order to consult the content of this Master's Degree, students only need an electronic device with an Internet connection. Thus, without schedules or attendance, students have the possibility of connecting whenever and wherever they wish.

TECH uses all of its technological tools to provide the most attractive multimedia content. Access it, whenever and wherever you want"

This Master's Degree in Human Microbiota contains the most complete and up-to-date scientific program on the market. The most important features include:

• Clinical cases presented by experts in Human Microbiota
• Its graphic, schematic and practical contents, with which they are conceived, gather scientific and assistance information on those disciplines that are essential for professional practice
• New diagnostic-therapeutic developments on assessment, diagnosis, and intervention in problems or disorders related to the Microbiota 
• Contains practical exercises, where the process of self-assessment can be carried out to improve learning
• An algorithm-based interactive learning system for decision-making in the clinical situations presented throughout the course
• With special emphasis on evidence-based medicine and research methodologies in Human Microbiota
• All of this will be complemented by theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments
• Content that is accessible from any fixed or portable device with an Internet connection

You will be able to get up to date easily and with the best team of professionals on scientific advances in the improvement of the musculoskeletal system through an adequate microbiota"

The program’s teaching staff includes professionals from the sector who contribute their work experience to this educational program, as well as renowned specialists from leading societies and prestigious universities. 

Its multimedia content, developed with the latest educational technology, will provide the professional with situated and contextual learning, i.e., a simulated environment that will provide an immersion education programmed to learn in real situations. 

The design of this program focuses on Problem-Based Learning, by means of which the professional must try to solve the different professional practice situations that are presented throughout the academic course. For this purpose, the student will be assisted by an innovative interactive video system created by renowned experts.  

This 100% online Master's Degree in the Microbiota of the genitourinary tract and the current lines of research in this field will give you a deeper understanding of the microbiota of the genitourinary tract"

A university degree that provides you with the most recent scientific evidence on the involvement of the microbiota in digestive disorders and nutrient malabsorption problems"

TECH uses the latest technology applied to teaching in the development of the content of each of its educational programs. A plus of quality and innovation, which give dynamism and agility to the students. Thus, professionals who take this university course will have multimedia content that will allow them to learn more about the microbiota in neonatology and pediatrics, the oral microbiota, as well as the composition of the intestinal microbiota in the different stages of life.

Reduce the hours of study and progress more quickly in this program thanks to the Relearning system used by TECH"

Module 1. Microbiota. Microbiome. Metagenomics

1.1. Definition and Relationship Between Them 
1.2. Composition of the Microbiota: Types, Species and Strains 

1.2.1. Groups of Microorganisms that Interact with Humans: Bacteria, Fungi, Viruses, and Protozoa 
1.2.2. Key Concepts: Symbiosis, Commensalism, Mutualism, Parasitism 
1.2.3. Autochthonous Microbiota 

1.3. Different Human Microbiota. General Overview of Eubiosis and Dysbiosis 

1.3.1. Gastrointestinal Microbiota 
1.3.2. Oral Microbiota 
1.3.3. Skin Microbiota 
1.3.4. Respiratory Tract Microbiota 
1.3.5. Urinary Tract Microbiota 
1.3.6. Reproductive System Microbiota

1.4. Factors that Influence Microbiota Balance and Imbalance 

1.4.1. Diet and Lifestyle. Gut-Brain Axis 
1.4.2. Antibiotic Therapy 
1.4.3. Epigenetic-Microbiota Interaction. Endocrine Disruptors 
1.4.4. Probiotics, Prebiotics, Symbiotics. Concepts and Overviews 
1.4.5. Fecal Transplant, Latest Advances

Module 2. Gut Microbiota I. Intestinal homeostasis

2.1. Gut Microbiota Studies 

2.1.1. Projects MetaHIT, Meta-Biomed, MyNewGut, Human Microbiome Project 

2.2. Microbiota Composition 

2.2.1. Protective Microbiota (Lactobacillus, Bifidobacterium, Bacteroides) 
2.2.2. Immunomodulatory Microbiota (Enterococcus faecalis and Escherichia coli) 
2.2.3. Mucoprotective or Muconutritive Microbiota (Faecalibacterium prausnitzii and Akkermansia muciniphila) 
2.2.4. Microbiota with Proteolytic or Proinflammatory Activities (E. coli Biovare, Clostridium, Proteus, Pseudomonas, Enterobacter, Citrobacter, Klebsiella, Desulfovibrio, Bilophila) 
2.2.5. Fungal Microbiota (Candida, Geotrichum) 

2.3. Digestive System Physiology. Composition of the Microbiota in the Different Parts of the Digestive Tract. Resident Flora and Transient or Colonizing Flora. Sterile Areas in the Digestive Tract 

2.3.1. Esophageal Microbiota 

2.3.1.1. Healthy Individuals 
2.3.1.2. Patients (Gastric Reflux, Barrett's Esophagus, etc.)

2.3.2. Gastric Microbiota 

2.3.2.1. Healthy Individuals 
2.3.2.2. Patients (Gastric Ulcer, Gastric Cancer, MALT, etc) 

2.3.3. Gallbladder Microbiota 

2.3.3.1. Healthy Individuals 
2.3.3.2. Patients (Cholecystitis, Cholelithiasis, etc.) 

2.3.4. Small Intestine Microbiota 

2.3.4.1. Healthy Individuals 
2.3.4.2. Patients (Inflammatory Bowel Disease, Irritable Bowel Syndrome, etc.) 

2.3.5. Colon Microbiota 

2.3.5.1. Healthy Individuals. Enterotypes 
2.3.5.2. Patients (Inflammatory Bowel Disease, Crohn's Disease, Colon Carcinoma, Appendicitis, etc.. 

2.4. Gut Microbiota Functions: Metabolic. Nutritional and Trophic. Protective and Barrier. Immunological 

2.4.1. Interrelationships Between the Intestinal Microbiota and Distant Organs (Brain, Lung, Heart, Liver, Pancreas, etc.) 

2.5. Intestinal Mucosa and Mucosal Immune System 

2.5.1. Anatomy, Characteristics, and Functions (MALT, GALT, and BALT System) 

2.6. What is Intestinal Homeostasis? Role of Bacteria in Intestinal Homeostasis 

2.6.1. Effects on Digestion and Nutrition 
2.6.2. Defence Stimulation, Hindering Colonization by Pathogenic Microorganisms 
2.6.3. Production of Vitamin B and K 
2.6.4. Production of Short Chain Fatty Acids (Butyric, Propionic, Acetic, etc.) 
2.6.5. Production of Gases (Methane, Carbon Dioxide, Molecular Hydrogen). Properties and Functions 
2.6.6. Lactic Acid 

Module 3. Gut Microbiota II. Intestinal Dysbiosis 

3.1. What is Intestinal Dysbiosis? Consequences 
3.2. Intestinal Barrier. Physiology. Function. Intestinal Permeability and Hyperpermeability. Relationship between Intestinal Dysbiosis and Intestinal Hyperpermeability 
3.3. Relationship of Intestinal Dysbiosis and Other Types of Disorders: Immunological, Metabolic, Neurological and Gastric (Helicobacter Pylori) 
3.4. Consequences of the Alteration of the Intestinal Ecosystem and its Relationship to Functional Digestive Disorders 

3.4.1. Inflammatory Bowel Disease IBD 
3.4.2. Chronic Inflammatory Bowel Diseases: Crohn's Disease. Ulcerative Colitis 
3.4.3. Irritable Bowel Syndrome (IBS) and Diverticulitis 
3.4.4. Intestinal Motility Disorders. Diarrhea. Diarrhea Caused by Clostridium Difficile. Constipation 
3.4.5. Digestive Disorders and Nutrient Malabsorption Problems: Carbohydrates, Proteins, and Fats 
3.4.6. Markers of Intestinal Inflammation: Calprotectin. Eosinophil Cationic Protein (ECP). Lactoferrin. Lysozyme. 
3.4.7. Leaky Gut Syndrome. Permeability Markers: Alpha-1 Antitrypsin. Zonulin. Tight Junctions and their Main Function. 

3.5. Alteration of the Intestinal Ecosystem and its Relationship with Intestinal Infections 

3.5.1. Viral Intestinal Infections 
3.5.2. Bacterial Intestinal Infections 
3.5.3. Intestinal Infections due to Parasites 
3.5.4. Fungal Intestinal Infections. Intestinal Candidiasis. 

3.6. Composition of the Intestinal Microbiota in the Different Stages of Life 

3.6.1. Variation in Gut Microbiota Composition from the Neonatal-Early Childhood Stage to Adolescence. “Unstable Period” 
3.6.2. Composition of the Intestinal Microbiota in Adulthood. “Stable Period” 
3.6.3. Gut Microbiota Composition in the Elderly "Unstable Stage". Aging and Microbiota 

3.7. Nutritional Modulation of Intestinal Dysbiosis and Hyperpermeability: Glutamine, Zinc, Vitamins, Probiotics, Prebiotics 
3.8. Techniques for Quantitative Analysis of Microorganisms in Feces 
3.9. Current Lines of Research 

Module 4. Microbiota in Neonatology and Pediatrics 

4.1. Mother-Child Symbiosis. 
4.2. Influencing Factors on the Gut Microbiota of the Mother during Pregnancy and during Birth. Influence of the Type of Delivery on the Microbiota of the New-born 
4.3. Type and Duration of Breastfeeding, Influence on the Infant’s Microbiota 

4.3.1. Breast Milk: Composition of the Breast Milk Microbiota. Importance of Breastfeeding in the New-born’s Microbiota 
4.3.2. Artificial Breastfeeding. Use of Probiotics and Prebiotics in Infant Milk Formulas 

4.4. Clinical Applications of Probiotics and Prebiotics in Pediatric Patients 

4.4.1. Digestive Diseases: Functional Digestive Disorders, Diarrhea, Necrotizing Enterocolitis. Intolerances 
4.4.2. Non-digestive Pathologies: Respiratory and ENT, Atopic Diseases, Metabolic Diseases. Allergies. 

4.5. Influence of Antibiotic and other Psychotropic Treatment on the Microbiota of the Infant. 
4.6. Current Lines of Research 

Module 5. Oral Microbiota and Respiratory Tract

5.1. Structure and Oral Ecosystems 

5.1.1. Main oral ecosystems 
5.1.2. Key Points 

5.2. Main Ecosystems that are Found in the Oral Cavity. Characteristics and Composition of Each of Them. Nostrils, Nasopharynx and Oropharynx 

5.2.1. Anatomical and histological features of the oral cavity 
5.2.2. Nasal Fossa 
5.2.3. Nasopharynx and oropharynx 

5.3. Alterations of the Oral Microbial Ecosystem: Oral Dysbiosis. Relationship with Different Oral Disease States 

5.3.1. Characteristics of Oral Microbiota 
5.3.2. Oral diseases 
5.3.3. Recommended measures to reduce dysbiotic processes 

5.4. Influence of External Agents in Oral Eubiosis and Dysbiosis. Hygiene 

5.4.1. Influence of External Agents in Oral Eubiosis and Dysbiosis. 
5.4.2. Oral symbiosis and dysbiosis 
5.4.3. Predisposing factors to oral dysbiosis 

5.5. Structure of the Respiratory Tract and Composition of the Microbiota and Microbiome 

5.5.1. Upper Respiratory Routes 
5.5.2. Lower Respiratory Routes 

5.6. Factors that Regulate the Respiratory Microbiota 

5.6.1. Metagenomics 
5.6.2. Hypothesis of Hygiene 
5.6.3. Viroma 
5.6.4. Microbiome or fungiome 
5.6.5. Probiotics in bronchial asthma 
5.6.6. Diet 
5.6.7. Prebiotics 
5.6.8. Bacterial translocation

5.7. Alteration of the Respiratory Tract Microbiota and its Relationship with Different Respiratory Tract Diseases 

5.7.1. Pathogenesis and clinical manifestations of upper respiratory tract infections 
5.7.2. Pathogenesis and clinical manifestations of upper respiratory tract infections 

5.8. Therapeutic Manipulation of the Microbiome of the Oral Cavity in Prevention and Treatment of Diseases Related to it 

5.8.1. Definition of Probiotics, Prebiotics, and Symbiotics 
5.8.2. Application for Oral Cavity Probiotic.. 
5.8.3. Probiotic strains used in the mouth 
5.8.4. Action in relation to oral diseases 

5.9. Therapeutic Manipulation of the Microbiome of the Respiratory Tract in Prevention and Treatment of Related Diseases 

5.9.1. Efficacy of probiotics for the treatment of respiratory tract disease: GI-Respiratory axis. 
5.9.2. Use of probiotics for the treatment of rhinosinusitis 
5.9.3. Use of probiotics for the treatment of Otitis 
5.9.4. Use of probiotics for the treatment of rhinosinusitis 
5.9.5. Use of probiotics in rhinitis and allergic bronchial asthma 
5.9.6. Probiotics to prevent lower respiratory tract infections 
5.9.7. Studies with lactobacilli 
5.9.8. Studies with bifidobacteria 

5.10. Current Lines of Research and Clinical Applications 

5.10.1. Transfer of fecal material 
5.10.2. Extraction of Nucleic Acids 
5.10.3. Sequencing Methods 
5.10.4. Strategies for Microbiota Characterization. 
5.10.5. Metataxonomy 
5.10.6. Metataxonomy of the Active Fraction 
5.10.7. Metagenomics 
5.10.8. Metabolomics 

Module 6. Microbiota and Immune System 

6.1. Immune System Physiology 

6.1.1. Immune System Components 

6.1.1.1. Lymphoid Tissue 
6.1.1.2. Immune Cells 
6.1.1.3. Chemical Systems 

6.1.2. Organs Involved in Immunity 

6.1.2.1. Primary Organs. 6.1.2.2. Secondary Organs. 

6.1.3. Innate, Non-Specific, or Natural Immunity 
6.1.4. Acquired, Adaptive, or Specific Immunity 

6.2. Nutrition and Lifestyle 
6.3. Functional Foods (Probiotics and Prebiotics), Nutraceuticals, and Immune System 

6.3.1. Probiotics, Prebiotics, and Symbiotics 
6.3.2. Nutraceuticals and Functional Foods 

6.4. Bidirectional Relationship between Microbiota and Neuroimmunoendocrine System 
6.5. Microbiota, Immunity and Nervous System Disorders: 
6.6. The Gut-Microbiota-Brain Axis 
6.7. Current Lines of Research 

Module 7. SkinMicrobiota

7.1. Skin Physiology 

7.1.1. Structure of the Skin: Epidermis, Dermis, and Hypodermis 
7.1.2. Functions of the Skin 
7.1.3. Microbial Composition of the Skin 

7.2. Factors that Regulate the Type of Bacterial Flora in the Skin 

7.2.1. Sweat Glands, Sebaceous Glands, Desquamation 
7.2.2. Factors that Alter the Ecology of the Skin and its Microbiota 

7.3. }Skin Immune System. Epidermis; Essential Element of our Defences 

7.3.1. Epidermis; Essential Element of our Defences 
7.3.2. Elements of the Cutaneous Immune System: Cytosines, Keratinocytes, Dendritic Cells, Lymphocytes, Antimicrobial Peptides 
7.3.3. Influence of the cutaneous microbiota on the skin immune system: Staphylococcus Epidermidis, Staphylococcus Aureus 

7.4. Alteration of the Normal Cutaneous Microbiota (Dysbiosis) and Alteration of the Barrier Function 

7.4.1. Impaired Barrier Function 

7.5. Triggered Skin Diseases 

7.5.1. Psoriasis (Streptococcus Pyogenes) 
7.5.2. Acne Vulgaris. 
7.5.3. Atopic Dermatitis. 
7.5.4. Rosacea. 

7.6. Influence of the use of Probiotics in the Prevention and Treatment of Different Skin Diseases 
7.7. Current Lines of Research 

Module 8. Genitourinary TractMicrobiota 

8.1. Physiology of the Genitourinary Tract in Men and Women

8.1.1. In Men 
8.1.2. In Women 

8.2. Microorganisms Causing Genitourinary Infections

8.2.1. Enteric Bacteria, Generally Gram-Negative Aerobic Bacteria: E. Coli, Enterobacteria. Klebsiella or Proteus Mirabilis or Pseudomonas Aeruginosa 
8.2.2. Gram-Positive Bacteria: Staphylococcus Saprophyticus, etc. 

8.3. Vaginal Microbiota and its Modification with Age 

8.3.1. Infant Age. 
8.3.2. Fertile Age 
8.3.3. Adult Age (Menopause) 

8.4. Alteration of the Vaginal Homeostasis and its Relationship with Infectious Pathologies 

8.4.1. Vaginitis.

8.4.1.1. Chlamydia.
8.4.1.2. Bacterial Vaginosis 
8.4.1.3. Vaginal Candidiasis.
8.4.1.4. Vaginitis Trichomoniasis.
8.4.1.5. Viral Vaginitis. 

8.4.2. Non-Infectious Vaginitis. 

8.5. Probiotics in the Prevention of the Main Genitourinary Tract Infections: UTI (Cystitis/Urethritis), Prostatitis, Pyelonephritis, Vaginal infections, and infertility 
8.6. Current Lines of Research 

Module 9. Relationship between Intolerances/Allergies and Microbiota 

9.1. Microbiota changes in Patients on Food Exclusion Diets 

9.1.1. Eosinophilic Esophagitis (EoE) 

9.2. Changes in the Microbiota in Patients with Food Exclusion Diets: Intolerance to Dairy Products (Lactose, Milk Proteins: Caseins, Albumins, Others)

9.2.1. Lactose Intolerance 
9.2.2. Intolerant to Lactic Proteins: Caseins, Albumins, etc. 
9.2.3. People Allergic to Milk 

9.3. Alteration and Recovery of the Intestinal Microbiota in Patients with Gluten Intolerance and Celiac Disease 

9.3.1. Alteration of the Intestinal Microbiota in Patients with Gluten Intolerance 
9.3.2. Alteration of the Intestinal Microbiota in Celiac Patients 
9.3.3. Role of Probiotics and Prebiotics in the Recovery of the Microbiota in Gluten Intolerant and Celiac Patients 

9.4. Microbiota and Biogenic Amines 
9.5. Current Lines of Research 

Module 10. Probiotics, Prebiotics, Microbiota, and Health 

10.1. Probiotics 
10.2. Prebiotics 
10.3. Clinical Applications of Probiotics and Prebiotics in Gastroenterology 
10.4. Clinical Applications of Endocrinology and Cardiovascular Disorders 
10.5. Clinical Applications of Probiotics and Prebiotics in Urology 
10.6. Clinical Applications of Probiotics and Prebiotics in Gynecology 
10.7. Clinical Applications of Probiotics and Prebiotics in Immunology 
10.8. Clinical Applications of Probiotics and Prebiotics in Nutritional Diseases 
10.9. Clinical Applications of Probiotics and Prebiotics in Neurological Diseases 
10.10. Clinical Applications of Probiotics and Prebiotics in Critically Ill Patients 
10.11. Dairy Products as a Natural Source of Probiotics and Prebiotics 
10.12. Safety and Legislation in the Use of Probiotics 

You are looking at a 100% online program that will provide you with the latest information on the mechanisms of action of probiotics and prebiotics"