Dr. Adriano Aguzzi is a leading specialist at European and international level, holding the position of director of the Swiss National Reference Center for Prion Diseases. From this institution, he delves into the diagnosis of Transmissible Spongiform Encephalopathies and develops his own therapeutic methods to address these pathologies from the thorough study of the immunological and molecular basis. 

Aguzzi's greatest scientific achievements are related to the discovery of the pathways by which prions reach the central nervous system through genetic manipulation of mice in vivo. In addition, his laboratory is committed to the development of state-of-the-art tissue clarification technologies with which microscopic images of complete rodent brains are obtained for 3D reconstruction with maximum precision. These techniques are promising for the academic community, allowing the characterization of vascular phenotypes in the context of stroke and neurodegenerative diseases such as Alzheimer's or Parkinson's disease.  

Among his many studies, his project Exploring the Locales of Cognitive Decline stands out. In it, Aguzzi proposes the combination of three-dimensional morphology with sophisticated fluorochrome chemistry and molecular methods of genome interrogation/perturbation. Through these revolutionary techniques, he aims to create a detailed atlas of the different cell types causing neurodegenerative damage. 

His avant-garde contributions have received a variety of awards. These include the Ernst-Jung Award, the Robert-Koch Award and an honorary medal from the European Molecular Biology Organization. He was also awarded the NOMIS Distinguished Scientist Award and has received Advanced grants from the European Research Council (ERC) to further his innovations. 

In addition, this distinguished neuroscientist is on the editorial board of Science and is editor-in-chief of the Swiss Medical Weekly. He is also a member of the advisory board of numerous philanthropic foundations and biomedical companies and serves as Director of the Institute of Neuropathology at the University of Zurich.  

• Director of the Swiss National Reference Center for Prion Diseases.
• Director of the Institute of Neuropathology, Zurich. 
• Professor at the University of Zurich 
• Editor-in-Chief of the Swiss Medical Weekly 
• Postdoctoral Fellow at the Research Institute for Molecular Pathology (IMP) in Vienna 
• Doctor of Medicine, Faculty of Medicine, University of Freiburg  
• Chairman of the Board of the European Brain Research Institute (EBRI) in Italy 
• Member of:  
  
  • Scientific Advisory Board of the Italian Institute of Technology in Genoa 
  • Advisory Board of the Giovanni Armenise-Harvard Foundation of Boston 
  • Neurosciences Committee of the Wellcome Trust, London 
  • Supervisory Board of the Roche Research Foundation