Understand the impact of Human Microbiota on the immune system, Metabolic and Digestive Diseases, and its role at every stage of life” 

The study of Human Microbiota has revolutionized the health field, revealing its key role in the prevention, diagnosis, and treatment of various diseases. Its influence on the immune system, Metabolic Diseases, Digestive Disorders, and even Neurological conditions has generated increasing interest in both clinical and research settings. Understanding these mechanisms is essential for health professionals who seek to stay updated and apply this knowledge in their daily practice, improving the quality of life of their patients.

This Master's Degree in Human Microbiota offers a unique opportunity to delve into a rapidly expanding field. Through rigorous and up-to-date content, specialists will gain a clinical perspective of the microbiota, exploring its relationship with different pathologies and its therapeutic potential. This will not only allow them to expand their competencies and strengthen their professional profile but also open new opportunities in research and specialization. In a context where personalized medicine and biotechnology are advancing quickly, mastering this field becomes a key competitive advantage.

Thanks to its 100% online format, this university program adapts to the needs of professionals who seek to continue growing without sacrificing their lifestyle. With flexible access to content and an innovative design, it ensures a dynamic and effective learning experience from anywhere, providing the highest academic quality without geographical restrictions.

Additionally, professionals will have access to exclusive Masterclasses led by internationally renowned guest directors in the medical field.

You will enjoy exclusive Masterclasses taught by renowned International Guest Directors” 

This Master's Degree in Human Microbiota contains the most complete and up-to-date scientific program on the market. The most important features include:

• The development of practical case studies presented by experts in Medicine
• The graphic, schematic, and practical contents with which they are created, provide scientific and practical information on the disciplines that are essential for professional practice
• Practical exercises where self-assessment can be used to improve learning
• Special emphasis on innovative methodologies in Medicine
• Theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments
• Content that is accessible from any fixed or portable device with an Internet connection

You will deepen your scientific knowledge of the Human Microbiota, its composition, functions, and its relationship with health” 

The teaching staff includes professionals belonging to the field of medicine, who contribute their work experience to this program, as well as renowned specialists from reference societies and prestigious universities.

Its multimedia content, created with the latest educational technology, will provide professionals with situated and contextualized learning—meaning a simulated environment that will offer immersive study designed to train you for real-life situations.

This program is designed around Problem-Based Learning, whereby the student must try to solve the different professional practice situations that arise throughout the program. For this purpose, the professional will be assisted by an innovative interactive video system created by renowned and experienced experts.

You will understand the interactions between the Microbiota and the various systems of the body, including the immune system” 

With the Relearning system you will not have to invest a great amount of study hours and you will focus on the most relevant concepts”

The Human Microbiota is an invisible universe with a massive impact on health. Its influence on the immune system, digestion, and even mental well-being makes it a key area for modern medicine. For this reason, this curriculum offers you a comprehensive journey through its clinical applications, from its connection to Chronic Diseases to its role in nutrition and immune response. With a practical approach based on the most recent evidence, this university program will allow medical professionals to specialize in a growing field and expand their opportunities in the Medical sector. 

You will delve into the interpretation of Microbiota analysis tests and their application in medical diagnosis” 

Module 1. Microbiota. Microbiome. Metagenomics

1.1. Definition and Relationship Between Them
1.2. Composition of the Microbiota: Types, Species and Strains
1.3. Different Human Microbiota. General Overview of Eubiosis and Dysbiosis

1.3.1. Gastrointestinal Microbiota
1.3.2. Oral Microbiota
1.3.3. Skin Microbiota
1.3.4. Respiratory Tract Microbiota
1.3.5. Urinary Tract Microbiota
1.3.6. Reproductive System Microbiota

1.4. Factors that Influence Microbiota Balance and Imbalance

1.4.1. Diet and Lifestyle. Gut-Brain Axis
1.4.2. Antibiotic Therapy
1.4.3. Epigenetic-Microbiota Interaction. Endocrine Disruptors
1.4.4. Probiotics, Prebiotics, Symbiotics. Concepts and Overviews
1.4.5. Fecal Transplant, Latest Advances

Module 2. Gut Microbiota I. Intestinal Homeostasis

2.1. Gut Microbiota Studies

2.1.1. Projects MetaHIT, Meta-Biomed, MyNewGut, Human Microbiome Project

2.2. Microbiota Composition

2.2.1. Protective Microbiota (Lactobacillus, Bifidobacterium, Bacteroides)
2.2.2. Immunomodulatory Microbiota (Enterococcus faecalis and Escherichia coli)
2.2.3. Mucoprotective or Muconutritive Microbiota (Faecalibacterium prausnitzii and Akkermansia muciniphila)
2.2.4. Microbiota with Proteolytic or Proinflammatory Activities (E. coli Biovare, Clostridium, Proteus, Pseudomonas, Enterobacter, Citrobacter, Klebsiella, Desulfovibrio, Bilophila)
2.2.5. Fungal Microbiota (Candida, Geotrichum)

2.3. Digestive System Physiology. Composition of the Microbiota in the Different Parts of the Digestive Tract. Resident Flora and Transient or Colonizing Flora. Sterile Areas in the Digestive Tract

2.3.1. Esophageal Microbiota

2.3.1.1. Healthy Individuals
2.3.1.2. Patients (Gastric Reflux, Barrett’s Esophagus, etc.)

2.3.2. Gastric Microbiota

2.3.2.1. Healthy Individuals
2.3.2.2. Patients (Gastric Ulcer, Gastric Cancer, MALT, etc)

2.3.3. Gallbladder Microbiota

2.3.3.1. Healthy Individuals
2.3.3.2. Patients (Cholecystitis, Cholelithiasis, etc.)

2.3.4. Small Intestine Microbiota

2.3.4.1. Healthy Individuals
2.3.4.2. Patients (Inflammatory Bowel Disease, Irritable Bowel Syndrome, etc.)

2.3.5. Colon Microbiota

2.3.5.1. Healthy Individuals. Enterotypes
2.3.5.2. Patients (Inflammatory Bowel Disease, Crohn’s Disease, Colon Carcinoma, Appendicitis, etc

2.4. Gut Microbiota Functions: Metabolic. Nutritional and Trophic. Protective and Barrier Immunological

2.4.1. Interrelationships Between the Intestinal Microbiota and Distant Organs (Brain, Lung, Heart, Liver, Pancreas, etc.)

2.5. Intestinal Mucosa and Mucosal Immune System

2.5.1. Anatomy, Characteristics, and Functions (MALT, GALT, and BALT System)

2.6. What is Intestinal Homeostasis? Role of Bacteria in Intestinal Homeostasis

2.6.1. Effects on Digestion and Nutrition
2.6.2. Defence Stimulation, Hindering Colonization by Pathogenic Microorganisms
2.6.3. Production of Vitamin B and K
2.6.4. Production of Short Chain Fatty Acids (Butyric, Propionic, Acetic, etc.)
2.6.5. Production of Gases (Methane, Carbon Dioxide, Molecular Hydrogen). Properties and Functions
2.6.6. Lactic Acid

Module 3. Gut Microbiota II. Intestinal Dysbiosis

3.1. What is Intestinal Dysbiosis? Consequences
3.2. Intestinal Barrier. Physiology. Function. Intestinal Permeability and Hyperpermeability. Relationship between Intestinal Dysbiosis and Intestinal Hyperpermeability
3.3. Relationship of Intestinal Dysbiosis and Other Types of Disorders: Immunological, Metabolic, Neurological and Gastric (Helicobacter Pylori)
3.4. Consequences of the Alteration of the Intestinal Ecosystem and its Relationship to Functional Digestive Disorders

3.4.1. Inflammatory Bowel Disease IBD
3.4.2. Chronic Inflammatory Bowel Diseases: Crohn’s Disease. Ulcerative Colitis
3.4.3. Irritable Bowel Syndrome (IBS) and Diverticulosis
3.4.4. Intestinal Motility Disorders. Diarrhea. Diarrhea Caused by Clostridium Difficile. Constipation
3.4.5. Digestive Disorders and Nutrient Malabsorption Problems: Carbohydrates, Proteins, and Fats
3.4.6. Markers of Intestinal Inflammation: Calprotectin. Eosinophil Cationic Protein (ECP). Lactoferrin. Lysozyme
3.4.7. Leaky Gut Syndrome. Permeability Markers: Alpha-1 Antitrypsin. Tight Junctions and their Main Function

3.5. Alteration of the Intestinal Ecosystem and its Relationship with Intestinal Infections

3.5.1. Viral Intestinal Infections
3.5.2. Bacterial Intestinal Infections
3.5.3. Intestinal Infections due to Parasites
3.5.4. Fungal Intestinal Infections. Intestinal Candidiasis

3.6. Composition of the Intestinal Microbiota in the Different Stages of Life

3.6.1. Variation in Gut Microbiota Composition , from the NeonatalEarly Childhood Stage to Adolescence. “Unstable Period”
3.6.2. Composition of the Intestinal Microbiota in Adulthood. “Stable Period”
3.6.3. Gut Microbiota Composition in the Elderly “Unstable Stage” Aging and Microbiota

3.7. Nutritional Modulation of Intestinal Dysbiosis and Hyperpermeability: Glutamine, Zinc, Vitamins, Probiotics, Prebiotics
3.8. Techniques for Quantitative Analysis of Microorganisms in Feces
3.9. Current Lines of Research

Module 4. Microbiota in Neonatology and Pediatrics

4.1. Mother-Child Symbiosis
4.2. Influencing Factors on the Gut Microbiota of the Mother During Pregnancy and During Birth. Influence of the Type of Delivery on the Microbiota of the New-born
4.3. Type and Duration of Breastfeeding, Influence on the Infant’s Microbiota

4.3.1. Breast Milk: Composition of the Breast Milk Microbiota. Importance of Breastfeeding in the New-born’s Microbiota
4.3.2. Artificial Breastfeeding. Use of Probiotics and Prebiotics in Infant Milk Formulas

4.4. Clinical Applications of Probiotics and Prebiotics in Pediatric Patients

4.4.1. Digestive Pathologies: Functional Digestive Disorders, Diarrhea, Necrotizing Enterocolitis. Intolerances
4.4.2. Non-digestive Pathologies: Respiratory and ENT, Atopic Diseases, Metabolic Diseases. Allergies

4.5. Influence of Antibiotic and other Psychotropic Treatment on the Microbiota of the Infant
4.6. Current Lines of Research

Module 5. Oral Microbiota and Respiratory Tract

5.1. Structure and Oral Ecosystems

5.1.1. Main Ecosystems that are Found in the Oral Cavity. Characteristics and Composition of Each of Them. Nostrils, Nasopharynx and Oropharynx

5.2. Alterations of the Oral Microbial Ecosystem: Oral Dysbiosis. Relationship with Different Oral Disease States

5.2.1. Cavities
5.2.2. Halitosis
5.2.3. Periodontal and Gingival Diseases
5.2.4. Peri-Implant Diseases
5.2.5. Other Infectious Diseases: Candida Albicans

5.3. Influence of External Agents in Oral Eubiosis and Dysbiosis. Hygiene
5.4. Structure of the Respiratory Tract and Composition of the Microbiota and Microbiome

5.4.1. Upper Respiratory Tract (Nasopharynx, Middle Ear, Sinuses, and Tonsils)
5.4.2. Lower Respiratory Tract (Trachea, Lungs, Bronchi, Bronchioles, and Alveoli)

5.5. Factors that Regulate the Respiratory Microbiota: Microbial Immigration, Microbial Elimination and Reproduction Rates of its Members

5.5.1. Microbial Immigration
5.5.2. Elimination of Microbes and the Reproduction Rates of its Members

5.6. Alteration of the Respiratory Tract Microbiota and its Relationship with Different Respiratory Tract Diseases
5.7. Therapeutic Manipulation of the Microbiome of the Oral Cavity in Prevention and Treatment of Diseases Related to it
5.8. Therapeutic Manipulation of the Microbiome of the Respiratory Tract in Prevention and Treatment of Related Diseases
5.9. Current Lines of Research and Clinical Applications

Module 6. Microbiota and the Immune System

6.1. Immune System Physiology: What is Immunity?

6.1.1. Immune System Components

6.1.1.1. Lymphoid Tissue
6.1.1.2. Immune Cells
6.1.1.3. Chemical Systems

6.2. Organs Involved in Immunity

6.2.1. Primary Organs
6.2.2. Secondary Organs

6.3. Innate, Non-Specific, or Natural Immunity
6.4. Acquired, Adaptive, or Specific Immunity
6.5. Nutrition and Lifestyle and their Interaction with the Immune System and the Microbiota
6.6. Functional Foods and their Effect on the Immune System

6.6.1. Probiotics, Prebiotics and Symbiotics
6.6.2. Nutraceuticals and Functional Foods

6.7. Bidirectional Relationship between Microbiota and Neuroimmunoendocrine System
6.8. Microbiota, Immunity, and Nervous System Disorders: Anxiety, Depression, Autism, Schizophrenia, or Alzheimer’s Disease
6.9. The Gut-Microbiota-Brain Axis
6.10. Current Lines of Research
6.11. Microbiota, Immunity, and Nervous System Disorders: Anxiety, Depression, Autism, Schizophrenia, or Alzheimer’s Disease
6.12. The Gut-Microbiota-Brain Axis
6.13. Current Lines of Research

Module 7. Skin Microbiota

7.1. Skin Physiology

7.1.1. Structure of the Skin: Epidermis, Dermis, and Hypodermis
7.1.2. Functions of the Skin
7.1.3. Microbial Composition of the Skin

7.2. Factors that Regulate the Type of Bacterial Flora in the Skin

7.2.1. Sweat Glands, Sebaceous Glands, Desquamation
7.2.2. Factors that Alter the Ecology of the Skin and Its Microbiota

7.3. Skin Immune System

7.3.1. Epidermis, Essential Element of Our Defenses
7.3.2. Elements of the Skin Immune System: Cytokines, Keratinocytes, Dendritic Cells, Lymphocytes, Antimicrobial Peptides
7.3.3. Influence of the Skin Microbiota on the Skin Immune System. Staphylococcus Epidermidis, Staphylococcus Aureus

7.4. Alteration of the Normal Skin Microbiota (Dysbiosis)

7.4.1. Impaired Barrier Function

7.5. Triggered Skin Diseases

7.5.1. Psoriasis (Streptococcus Pyogenes)
7.5.2. Acne Vulgaris
7.5.3. Atopic Dermatitis
7.5.4. Rosacea

7.6. Influence of the Use of Probiotics in the Prevention and Treatment of Different Skin Diseases
7.7. Current Lines of Research

Module 8. Genitourinary Tract Microbiota

8.1. Genitourinary Tract Physiology and Microbial Composition

8.1.1. In Men
8.1.2. In Women

8.2. Microorganisms Causing Urinary Tract Infections: Uropathogens. Relationship with the Alteration of the Microbiota in Men and Women

8.2.1. Enteric Bacteria, Generally Gram-Negative Aerobic Bacteria: E. Coli, Enterobacteria. Klebsiella or Proteus Mirabilis or Pseudomonas Aeruginosa
8.2.2. Gram-Positive Bacteria: Staphylococcus Saprophyticus, etc

8.3. Vaginal Microbiota and its Modification with Age

8.3.1. Infant Age
8.3.2. Fertile Age
8.3.3. Adult Age (Menopause)

8.4. Alteration of the Vaginal Homeostasis and its Relationship with Infectious Pathologies

8.4.1. Vaginitis

8.4.1.1. Chlamydia
8.4.1.2. Bacterial Vaginosis
8.4.1.3. Vaginal Candidiasis
8.4.1.4. Vaginal Tricomoniasis
8.4.1.5. Viral Vaginitis

8.4.2. Non-Infectious Vaginitis

8.5. Probiotics in the Prevention of the Main Genitourinary Tract Infections: UTI (Cystitis/Urethritis), Prostatitis, Pyelonephritis, Vaginal infections, and infertility
8.6. Current Lines of Research

Module 9. Relationship Between Intolerances/Allergies and Microbiota

9.1. Microbiota Changes in Patients on Food Exclusion Diets

9.1.1. Eosinophilic Esophagitis (EoE)

9.2. Microbiota Changes in Patients on Food Exclusion Diets: Intolerance to Dairy

9.2.1. Lactose Intolerance
9.2.2. Intolerant to Lactic Proteins: Caseins, Albumins, etc
9.2.3. People Allergic to Milk

9.3. Microbiota Changes in Patients on Food Exclusion Diets: Gluten

9.3.1. Alteration of the Intestinal Microbiota in Patients with Gluten Intolerance
9.3.2. Alteration of the Intestinal Microbiota in Celiac Patients
9.3.3. Role of Probiotics and Prebiotics in the Recovery of the Microbiota in Gluten Intolerant and Celiacs

9.4. Microbiota and Biogenic Amines
9.5. Current Lines of Research

Module 10. Probiotics, Prebiotics, Microbiota and Health

10.1. Probiotics: Definition, History, Mechanisms of Action
10.2. Prebiotics: Definition, Types of Prebiotics (Starch, Inulin, FOS Oligosaccharides), Mechanisms of Action
10.3. Clinical Applications of Probiotics and Prebiotics in Gastroenterology
10.4. Clinical Applications of Endocrinology and Cardiovascular Disorders
10.5. Clinical Applications of Probiotics and Prebiotics in Urology
10.6. Clinical Applications of Probiotics and Prebiotics in Gynecology
10.7. Clinical Applications of Probiotics and Prebiotics in Immunology: Autoimmunity, Pulmonology, Vaccines
10.8. Clinical Applications of Probiotics and Prebiotics in Nutritional Diseases. Obesity and Eating Disorders. Metabolism, Malnutrition and Malabsorption of Nutrients
10.9. Clinical Applications of Probiotics and Prebiotics in Neurological Diseases. Mental Health. Old Age
10.10. Clinical Applications of Probiotics and Prebiotics in Critically Ill Patients. Cancer
10.11. Dairy Products as a Natural Source of Probiotics and Prebiotics. Fermented Milk

You will explore clinical intervention strategies such as the use of probiotics, prebiotics, symbiotics, and personalized nutrition”