The latest techniques and work systems in Genetics, Pathologies and Biobanks Network in the clinical analysis laboratory, with the most efficient teaching system on the market"

The research and techniques developed in genetics are very useful for the study of the cause, transmission and pathogenesis of numerous diseases. The objective of genetic medicine is to understand the different types of genetic alterations that give rise to diseases, analyze their transmission, identify carriers, and develop methods of prevention and treatment. In the laboratory, this study takes place in a practical way in the most important and specific developments in this area of work. 

This module provides an in-depth analysis of the bases and mechanisms of the transmission of genetic material, with special attention to the particularities and characteristics of human genetics: the different genetic alterations that can give rise to diseases, the techniques and methods for diagnosing them, as well as the latest advances and research carried out in this field. All of this in the field of clinical analysis laboratories. 

A compendium and deepening of knowledge that will lead you to excellence in your profession.

With this Course you will be able to combine high intensity training with your personal and professional life, achieving your goals in a simple and real way”

This Postgraduate certificate in Genetics, Pathologies and Biobanks Network offers you the characteristics of a high-level scientific, teaching, and technological course.  These are some of its most notable features: 

• Latest technology in online teaching software
• Highly visual teaching system, supported by graphic and schematic contents that are easy to assimilate and understand
• Practical cases presented by practising experts
• State-of-the-art interactive video systems
• Teaching supported by telepractice
• Continuous updating and recycling systems
• Self-regulating learning: full compatibility with other occupations
• Practical exercises for self-evaluation and learning verification
• Support groups and educational synergies: questions to the expert, debate and knowledge forums
• Communication with the teacher and individual reflection work
• Content that is accessible from any fixed or portable device with an Internet connection
• Supplementary documentation databases are permanently available, even after the course

A highly skilled course which will allow you to become a highly competent professional in genetics in a clinical analysis laboratory”

The teachers of this course are professionals currently working in a modern and accredited Clinical Laboratory, with a very solid training base and up to date knowledge in both scientific and purely technical disciplines. 

In this way, we ensure that we provide you with the training update we are aiming for. A multidisciplinary team of professionals trained and experienced in different environments, who will cover the theoretical knowledge in an efficient way, but, above all, will put the practical knowledge derived from their own experience at the service of the course: one of the differential qualities of this course. 

This mastery of the subject is complemented by the effectiveness of the methodological design of this course in Genetics, Pathologies and Biobanks Network. Developed by a multidisciplinary team of experts, it integrates the latest advances in educational technology. In this way, you will be able to study with a range of easy-to-use and versatile multimedia tools that will give you the necessary skills you need for your specialization.  

The design of this program is based on Problem-Based Learning: an approach that conceives learning as a highly practical process. To achieve this remotely, we will use telepractice:  with the help of an innovative interactive video system, and learning from an expert, you will be able to acquire the knowledge as if you were actually dealing with the scenario you are learning about. A concept that will allow you to integrate and fix learning in a more realistic and permanent way. 

A program created and directed by active professionals who are experts in this field of work, which makes this course a unique opportunity for professional growth"

The learning in this Postgraduate certificate is developed through the most performed didactic methods in online teaching to guarantee that your efforts produce the best results possible"

The contents of this course have been developed by the different experts on this course, with a clear purpose: to ensure that our students acquire each and every one of the necessary skills to become true experts in this field.  

A complete and well-structured program that will take you to the highest standards of quality and success.   

A comprehensive and specific Postgraduate certificate that will boost your professional development with the assurance of the best training and the highest skill level”

Module 1. Genetics 

1.1. Introduction to Genetic Medicine Genealogies and Inheritance Patterns  

1.1.1. Historical Development of Genetics Key Concepts
1.1.2. Structure of Genes and Regulation of Genetic Expression Epigenetics 
1.1.3. Genetic Variability Mutation and Reparation of DNA 
1.1.4. Human Genetics Organization of the Human Genome 
1.1.5. Genetic Diseases Morbidity and Mortality 
1.1.6. Human Inheritance Concept of Genotype and Phenotype 

1.1.6.1. Mendelian Inheritance Patterns 
1.1.6.2. Multigene and Mitochondrial Inheritance 

1.1.7. Construction of Genealogies 

1.1.7.1. Allele, Genotypic and Phenotypic Frequency Estimation
1.1.7.2. Segregation Analysis 

1.1.8. Other Factors which Affect the Phenotype 

1.2. Molecular Biology Techniques Used in Genetics 

1.2.1. Genetics and Molecular Diagnostics 
1.2.2. Polymerase Chain Reaction (PCR) Applied to Diagnosis and Research in Genetics 

1.2.2.1. Detection and Amplification of Specific Sequences  
1.2.2.2. Quantification of Nucleic Acids (RT-PCR) 

1.2.3. Cloning Techniques: Isolation, Restriction and Ligation of DNA Fragments 
1.2.4. Detection of Mutations and Measurement of Genetic Variability: RFLP, VNTR, SNPs 
1.2.5. Mass Sequencing Techniques. NGS 
1.2.6. Transgenesis Genetic Therapy 
1.2.7. Cytogenetic Techniques 

1.2.7.1. Chromosome Banding 
1.2.7.2. FISH, CGH 

1.3. Human Cytogenetics Numerical and Structural Chromosomal Abnormalities 

1.3.1. Study of Human Cytogenetics Features 
1.3.2. Chromosome Characterization and Cytogenetic Nomenclature 

1.3.2.1. Chromosomal Analysis: Karyotype

1.3.3. Anamolies in the Number of Chromosones 

1.3.3.1. Polyploidies 
1.3.3.2. Aneuploidies 

1.3.4. Structural Chromosomal Alterations Genetic Dosis 

1.3.4.1. Deletions 
1.3.4.2. Duplications 
1.3.4.3. Inversions 
1.3.4.4. Translocations 

1.3.5. Chromosomal Polymorphisms 
1.3.6. Genetic Imprinting  

1.4. Prenatal Diagnosis of Genetic Alterations and Congenital Defects Preimplantational Genetic Diagnosis 

1.4.1. Prenatal Diagnosis. What does it entail? 
1.4.2. Incidence of Congenital Defects 
1.4.3. Indications for Performing Prenatal Diagnosis 
1.4.4. Prenatal Diagnostic Methods 

1.4.4.1. Non-Invasive Procedures: First and Second Trimester Screening TPNI 
1.4.4.2. Invasive Procedures: Amniocentesis, Cordocentesis and Chorionic Biopsy 

1.4.5. Preimplantational Genetic Diagnosis Indications
1.4.6. Embryo Biopsy and Genetic Analysis  

1.5. Genetic Diseases I 

1.5.1. Diseases with Autosomal Dominant Inheritance 

1.5.1.1. Achondroplasia 
1.5.1.2. Huntington's Disease 
1.5.1.3. Retinoblastoma 
1.5.1.4. Charcot-Marie-Tooth Disease 

1.5.2. Diseases with Autosomal Recessive Inheritance 

1.5.2.1. Phenylketonuria
1.5.2.2. Sickle Cell Anemia 
1.5.2.3. Cystic Fibrosis 
1.5.2.4. Laron Syndrome 

1.5.3. Diseases with Sex-Linked Inheritance 

1.5.3.1. Rett Sydrome 
1.5.3.2. Haemophilia 
1.5.3.3. Duchenne Muscular Dystrophy 

1.6. Genetic Diseases II 

1.6.1. Mitochondrial Inheritance Diseases 

1.6.1.1. Mitochondrial Encephalomyopathies 
1.6.1.2. Leber Hereditary Optic Neuropathy (NOHL) 

1.6.2. Genetic Anticipation Phenomena 

1.6.2.1. Huntington's Disease 
1.6.2.2. Fragile X Syndrome 
1.6.2.3. Spinocerebellar Ataxias 

1.6.3. Allelic Heterogeneity 

1.6.3.1. Usher Syndrome 

1.7. Complex Diseases Genetics Molecular Basis of Family and Sporadic Cancer 

1.7.1. Multifactorial Inheritance 

1.7.1.1. Polygenes 

1.7.2. Contribution of Environmental Factors on Complex Diseases 
1.7.3. Quantative Genetics 

1.7.3.1. Heritability 

1.7.4. Common Complex Diseases 

1.7.4.1. Diabetes Mellitus 
1.7.4.2. Alzheimer’s Disease 

1.7.5. Behavioral Diseases and Personality Disorders: Alcoholism, Autism and Schizophrenia 
1.7.6. Cancer: Molecular Base and Environmental Factors 

1.7.6.1. Genetics of Cell Proliferation and Differentiation Processes Cellular Cycle 
1.7.6.2. DNA Reparation Genes, Oncogenes and Tumor Suppresor Genes 
1.7.6.3. Environmental Influence of the Occurence of Cancer 

1.7.7. Familial Cancer 

1.8. Genomics and Proteomics 

1.8.1. Omic Sciences and their Usefulness in Medicine 
1.8.2. Genome Sequencing and Analysis 

1.8.2.1. DNA Libraries 

1.8.3. Comparative Genomics 

1.8.3.1. Organisms Model 
1.8.3.2. Sequencing Comparison 
1.8.3.3. Human Genome Project 

1.8.4. Functional Genomics

1.8.4.1. Transcriptomics 
1.8.4.2. Structural and Functional Organization of the Genome 
1.8.4.3. Functional Genomic Elements 

1.8.5. From the Genome to the Proteome 

1.8.5.1. Post-Translational Modifications 

1.8.6. Strategies for the Separation and Purification of Proteins  
1.8.7. Identification of Proteins 
1.8.8. Interactom 

1.9. Genetic Assessment Ethical and Legal Aspects of Diagnosis and Research in Genetics 

1.9.1. Genetic Assessment Concepts and Base Techniques 

1.9.1.1. Risk of Recurrence of Genetically-Based Diseases 
1.9.1.2. Genetic Assessment in Prenatal Diagnosis 
1.9.1.3. Ethical Principles in Genetic Assessment 

1.9.2. Legislation of New Genetic Technology 

1.9.2.1. Genetic Engineering 
1.9.2.2. Human Cloning 
1.9.2.3. Genetic Therapy 

1.9.3. Bioethics and Genetics 

1.10. Biobanks and Bioinformatics Tools 

1.10.1. Biobanks Concept and Functions 
1.10.2. Organization, Managament and Quality of Biobanks 
1.10.3. Spanish Network of Biobanks 
1.10.4. Computational Biology 
1.10.5. Big Data and Machine Learning 
1.10.6. Bioinformatics Applications in Biomedicine 

1.10.6.1. Sequences Analysis 
1.10.6.2. Image Analysis 
1.10.6.2. Personalized and Precision Medicine  

A unique, key, and decisive specialization experience to boost your professional development”