Update your knowledge and care techniques in Genomic and Precision Nutrition through this program, which includes an intensive clinical stay in a reference health center"

Genomic and Precision Nutrition has experienced great progress in recent years thanks to the numerous scientific and technological discoveries in this area. Currently, more effective dietary supplements and intervention and prevention strategies for diseases such as hypertension or type II diabetes have been developed based on the interaction of certain genes with specific nutrients. To apply these techniques and benefits efficiently, it is essential that nursing professionals possess the most up-to-date knowledge and skills in the field.

To respond to this context, TECH has created this Hybrid professional master’s degree that focuses on teaching the latest advances in Genomic and Precision Nutrition. The educational methodology used in this program is hybrid, combining theoretical and practical learning with a practical stay in a prestigious center. Therefore, the first part of the teaching is carried out on an interactive platform, 100% online, with valuable multimedia resources such as infographics and videos. In addition, innovative methodologies, such as Relearning, are used to facilitate the understanding of the most complex concepts.

After the theoretical phase, TECH offers a 120-hour clinical internship in a renowned hospital institution. During this period, students will apply the theoretical knowledge acquired on real patients and in the most complex clinical scenarios. To ensure the correct application of these techniques, an assistant tutor is assigned to provide support at all times. The practical stay lasts three weeks, with 8-hour workdays. At the end of the process, students will be ready to apply the main innovations of Genomic and Precision Nutrition in their daily nursing practice.

Master the most advanced procedures in Genomic Nutrition thanks to this Advanced Master's Degree, with which you will be able to put into practice the latest techniques in nutritional counseling"

This Hybrid professional master’s degree in Genomic and Precision Nutrition for Nursing contains the most complete and up-to-date scientific program on the market. The most important features include: 

• The development of more than 100 clinical cases presented by experts in Genomic and Precision Nutrition
• The graphic, schematic, and practical contents with which they are created, provide scientific and practical information on the disciplines that are essential for professional practice
•  An algorithm-based interactive learning system for decision-making in the clinical situations presented throughout the course
• Clinical practice guidelines on the approach to the different pathologies from Genomic Nutrition
• All this will be complemented by theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments
• Content that is accessible from any fixed or portable device with an Internet connection
• In addition, you will be able to carry out a clinical internship in one of the best hospitals in the world

TECH has carefully selected the most prestigious training centers to enable you to train in a high-level clinical environment”

In this Professional Master's Degree proposal, of a professionalizing nature and hybrid modality, the program is aimed at updating nursing professionals who require a high level of qualification. The content is based on the latest scientific evidence and is organized in a didactic way to integrate theoretical knowledge into nursing practice. The theoretical-practical elements allow professionals to update their knowledge and help them to make the right decisions in patient care.

Thanks to their multimedia content developed with the latest educational technology, they will allow the nursing professional to obtain situated and contextual learning, i.e., a simulated environment that will provide immersive learning programmed to train in real situations. This program is designed around Problem-Based Learning, whereby the physician must try to solve the different professional practice situations that arise during the course. For this purpose, it will be aided by an innovative interactive video system developed by renowned experts.

Get up to date to be at the forefront of personalized health care, being able to design patient-specific nutritional plans"

The hybrid nature of this program will allow you to study at your own pace and in a 100% online format and then apply what you have learned in a prestigious center"

This program has a complete syllabus focused on the study of the most innovative and updated tools in the field of Genomic and Precision Nutrition. Throughout the program, students will have access to high-level theoretical and practical knowledge that will enable them to acquire up-to-date skills in the application of these tools in their daily practice.

You are looking at the most comprehensive syllabus on Genomic and Precision Nutrition oriented to Nursing. Enroll now”

Module 1. Introduction to Nutritional Genomics and Precision Nutrition

1.1. Human Genome

1.1.1. DNA Discovery
1.1.2. Year 2001
1.1.3. Human Genome Project

1.2. Variations of Interest in Nutrition

1.2.1. Genomic Variations and the Search for Disease Genes
1.2.2. Environment vs. Genetic Factor and Heritability
1.2.3. Differences between SNPs, Mutations and CNVs

1.3. The Genome of Rare and Complex Diseases

1.3.1. Examples of Rare Diseases
1.3.2. Examples of Complex Diseases
1.3.3. Genotype and Phenotype

1.4. Precision Medicine

1.4.1. Influence of Genetics and Environmental Factors on Complex Diseases
1.4.2. Need for Precision The problem of Missing Heritability Concept of Interaction

1.5. Precision Nutrition vs. Community Nutrition

1.5.1. The Principles of Nutritional Epidemiology
1.5.2. Current Bases of Nutritional Research
1.5.3. Experimental Designs in Precision Nutrition

1.6. Levels of Scientific Evidence

1.6.1. Epidemiological Pyramid
1.6.2. Regulation
1.6.3. Official Guides

1.7. Consortia and Major Studies in Human Nutrition and Genomic Nutrition

1.7.1. Precision4Health Project
1.7.2. Framingham
1.7.3. PREDIMED
1.7.4. CORDIOPREV

1.8. Current European Studies

1.8.1. PREDIMED Plus
1.8.2. NU-AGE
1.8.3. FOOD4me
1.8.4. EPIC

Module 2. Laboratory Techniques for Nutritional Genomics

2.1. Molecular Biology Laboratory

2.1.1. Basic Instructions
2.1.2. Basic Material
2.1.3. Accreditations Required in the U.S.

2.2. DNA Extraction

2.2.1. From Saliva
2.2.2. From Blood
2.2.3. From Other Fabrics

2.3. Real-Time PCR

2.3.1. Introduction - History of the Method
2.3.2. Basic Protocols Used
2.3.3. Most Used Equipment

2.4. Sequencing

2.4.1. Introduction - History of the Method
2.4.2. Basic Protocols Used
2.4.3. Most Used Equipment

2.5. High-throughput

2.5.1. Introduction - History of the Method
2.5.2. Examples of Human Studies

2.6. Gene Expression - Genomics - Transcriptomics

2.6.1. Introduction - History of the Method
2.6.2. Microarrays
2.6.3. Microfluidic Cards
2.6.4. Examples of Human Studies

2.7. Omics Technologies and their Biomarkers

2.7.1. Epigenomics
2.7.2. Proteomics
2.7.3. Metabolomics
2.7.4. Metagenomics

2.8. Bioinformatics Analysis

2.8.1. Pre- and Post-Computing Bioinformatics Programs and Tools
2.8.2. GO Terms, Clustering of DNA Microarray Data
2.8.3. Functional Enrichment, GEPAS, Babelomics

Module 3. Biostatistics for Genomic Nutrition

3.1. Biostatistics

3.1.1. Human Studies Methodology
3.1.2. Introduction to Experimental Design
3.1.3. Estudios clínicos

3.2. Statistical Aspects of a Protocol

3.2.1. Introduction, Objectives, Description of Variables
3.2.2. Quantitative Variables
3.2.3. Qualitative Variables

3.3. Design of Clinical Studies in Humans, Methodological Guidelines

3.3.1. Designs with 2 treatments 2x2
3.3.2. Designs with 3 treatments 3x3
3.3.3. Parallel, Cross-Over, Adaptive Design
3.3.4. Sample Size Determination and Power Analysis

3.4. Evaluation of Treatment Effect

3.4.1. For Parallel Design, for Repeated Measurements, for Cross-Over Design
3.4.2. Randomization of the Order of Treatment Assignment
3.4.3. Carry-Over Effect (Wash Out)

3.5. Descriptive Statistics, Hypothesis Testing, Risk Calculation

3.5.1. Consort, Populations
3.5.2. Study Populations
3.5.3. Grupo control
3.5.4. Subgroup Analysis Types of Studies

3.6. Statistical Errors

3.6.1. Measurement Errors
3.6.2. Random Error
3.6.3. Systematic Error

3.7. Statistical Bias

3.7.1. Selection Bias
3.7.2. Observation Bias
3.7.3. Sesgo de asignación

3.8. Statistical Modeling

3.8.1. Continuous Variable Models
3.8.2. Categorical Variables Models
3.8.3. Linear Mixed Models
3.8.4. Missing data, Flow of Participants, Presentation of Results
3.8.5. Adjustment for Baseline Values, Transformation of Response Variable: Differences, Ratios, Logarithms, Carry-Over Evaluation

3.9. Statistical Modeling with Co-Variables

3.9.1. ANCOVA
3.9.2. Logistic Regression for Binary and Count Variables
3.9.3. Multi-Variant Analysis

3:10. Statistical Programs

3.10.1. The R
3.10.2. SPSS

Module 4. Nutrigenetics I

4.1. Nutrigenetics Authorities and Organizations

4.1.1. NUGO
4.1.2. ISNN
4.1.3. Evaluation Committees

4.2. GWAS I Studies

4.2.1. Population Genetics - Design and Use
4.2.2. Hardy-Weinberg Law
4.2.3. Linkage Imbalance

4.3. GWAS II

4.3.1. Allelic and Genotypic Frequencies
4.3.2. Gene-Disease Association Studies
4.3.3. Association Models ( Dominant, Recessive, Co-dominant)
4.3.4. Genetic Scores

4.4. The Discovery of Nutrition-Related SNPs

4.4.1. Key Studies-Design
4.4.2. Main Results

4.5. The Discovery of SNPs Associated with Nutrition-Related Diseases (Diet-Depended)

4.5.1. Cardiovascular Diseases.
4.5.2. Diabetes Mellitus Type II
4.5.3. Metabolic Syndrome

4.6. Main Obesity-Related GWAS

4.6.1. Strengths and Weaknesses
4.6.2. The FTO Example

4.7. Circadian Control of Intake

4.7.1. Gut-Brain Axis
4.7.2. Molecular and Neurological Basis of the Brain-Gut Connection

4.8. Chronobiology and Nutrition

4.8.1. Central Clock
4.8.2. Peripheral Clocks
4.8.3. Circadian Rhythm Hormones
4.8.4. Intake Control (Leptin and Ghrelin)

4.9. SNPs Related to Circadian Rhythms

4.9.1. Regulatory Mechanisms of Satiety
4.9.2. Hormones and Intake Control
4.9.3. Possible Pathways Involved

Module 5. Nutrigenetics II - Key Polymorphisms

5.1. Obesity-Related SNPs

5.1.1. The Tale of the Obese Monkey
5.1.2. Appetite Hormones
5.1.3. Thermogenesis

5.2. Vitamin-Related SNPs

5.2.1. Vitamin D
5.2.2. B Complex Vitamins
5.2.3. Vitamin E

5.3. Exercise-Related SNPs

5.3.1. Strength vs. Competition
5.3.2. Sports Performance
5.3.3. Injury Prevention/Recovery

5.4. Oxidative Stress/Detoxification-related SNPs

5.4.1. Genes Encoding Enzymes
5.4.2. Anti-Inflammatory Processes
5.4.3. Phase I+II of Detoxification

5.5. SNP related to Addictions

5.5.1. Caffeine
5.5.2. Alcohol
5.5.3. Salt

5.6. SNP related to Flavor

5.6.1. Sweet Taste
5.6.2. Salty Taste
5.6.3. Bitter Taste
5.6.4. Acid Taste

5.7. SNP vs Allergies vs Intolerances

5.7.1. Lactose
5.7.2. Gluten
5.7.3. Fructose

5.8. PESA Study

Module 6. Nutrigenetics III

6.1. SNPs Predisposing to Complex Nutrition-Related Diseases - Genetic Risk Scores (GRS)
6.2. Type II Diabetes
6.3. Hypertension
6.4. Arteriosclerosis
6.5. Hyperlipidemia
6.6. Cancer
6.7. The Exposome Concept
6.8. Metabolic Flexibility Concept
6.9. Current Studies-Challenges for the Future

Module 7. Nutrigenomics

7.1. Differences and Similarities with Nutrigenetics
7.2. Bioactive Components of Diet on Gene Expression
7.3. The Effect of Micro and Macro Nutrients on Gene Expression
7.4. The Effect of Dietary Patterns on Gene Expression

7.4.1. The Mediterranean Diet Example

7.5. Main Studies in Gene Expression
7.6. Genes Related to Inflammation
7.7. Genes Related to Insulin Sensitivity
7.8. Genes related to Lipid Metabolism and Adipose Tissue Differentiation
7.9. Genes Related to Arteriosclerosis
7:10. Genes Related to the Myosceletal System

Module 8. Metabolomics-Proteomics

8.1. Proteomics

8.1.1. Principles of Proteomics
8.1.2. The Flow of Proteomics Analysis

8.2. Metabolomics

8.2.1. Principles of Metabolomics
8.2.2. Targeted Metabolomics
8.2.3. Non-Targeted Metabolomics

8.3. The Microbiome/Microbiota

8.3.1. Microbiome Data
8.3.2. Human Microbiota Composition
8.3.3. Enterotypes and Diet

8.4. Main Metabolomic Profiles

8.4.1. Application to Disease Diagnosis
8.4.2. Microbiota and Metabolic Syndrome
8.4.3. Microbiota and Cardiovascular Diseases Effect of the Oral and Intestinal Microbiota

8.5. Microbiota and Neurodegenerative Diseases

8.5.1. Alzheimer’s Disease
8.5.2. Parkinson’s Disease
8.5.3. ALS

8.6. Microbiota and Neuropsychiatric Diseases

8.6.1. Schizophrenia.
8.6.2. Anxiety, Depression, Autism

8.7. Microbiota and Obesity

8.7.1. Enterotypes
8.7.2. Current Studies and State of Knowledge

Module 9. Epigenetics

9.1. History of Epigenetics - The Way I Eat and Inheritance for My Grandchildren
9.2. Epigenetics vs Epigenomics
9.3. Methylation

9.3.1. Examples of Folate and Choline, Genistein
9.3.2. Examples of Zinc, Selenium, Vitamin A, Protein Restriction

9.4. Histone Modification

9.4.1. Examples of Butyrate, Isothiocyanates, Folate and Choline
9.4.2. Examples of Retinoic Acid, Protein Restriction

9.5. MicroRNA

9.5.1. Biogenesis of MicroRNAs in Humans
9.5.2. Mechanisms of Action-Regulating Processes

9.6. Nutrimiromics

9.6.1. Diet-Modulated MicroRNAs
9.6.2. MicroRNAs involved in Metabolism

9.7. Role of MicroRNAs in Diseases

9.7.1. MicroRNA in Tumorogenesis
9.7.2. MicroRNAs in Obesity, Diabetes and Cardiovascular Diseases

9.8. Gene Variants that Generate or Destroy Binding Sites for MicroRNAs

9.8.1. Main Studies
9.8.2. Results in Human Diseases

9.9. MicroRNA Detection and Purification Methods

9.9.1. Circulating MicroRNAs
9.9.2. Basic Methods Used

Module 10. Current Market State

10.1. Legal Aspects
10.2. DTC (Direct-to-Consumer) Tests

10.2.1. Pros and Cons
10.2.2. Myths of Early DTCs

10.3. Quality Criteria for a Nutrigenetic Test

10.3.1. SNP Selection
10.3.2. Interpretation of Results
10.3.3. Laboratory Accreditations

10.4. Health Professionals

10.4.1. Training Needs
10.4.2. Criteria of Professionals Applying Genomic Nutrition

10.5. Nutrigenomics in the Media
10.6. Integration of Evidence for Personalized Nutritional Counseling
10.7. Critical Analysis of the Current Situation
10.8. Discussion Work
10.9. Conclusions, use of Genomic and Precision Nutrition as Prevention

Progress professionally by becoming an expert in Genomic Nutrition and applying the most advanced care techniques"