With this 100% online Postgraduate diploma, you will immerse yourself in the causes and mechanisms of antibiotic resistance, as well as the health policies that influence its spread, facing this challenge effectively”

With the alarming increase in bacterial antibiotic resistance, clinical protocols have evolved towards a more personalized approach, using advanced molecular diagnostic techniques to rapidly identify pathogens and determine their resistance profiles. This integration of genomics and microbiology has enabled the development of targeted therapies and more effective prevention strategies. 

In this way, this university diploma was born, which will address in depth the problem of multidrug-resistant bacteria in human pathology, exploring from the roots of antibiotic resistance, to determining factors such as the scarcity of new antibiotics, socioeconomic influences and health policies. It will also examine the global situation of resistance, providing updated statistics and regional trends to better understand the scope of the problem worldwide. 

Furthermore, the syllabus will focus on the clinical management of patients with Multidrug-Resistant Infections in Intensive Care Units (ICU). Here, professionals will acquire specialized knowledge in diagnosis and treatment of frequent infections in critical settings, as well as advanced skills in the implementation of preventive measures to reduce the incidence and spread of these resistant bacteria within ICUs. 

Finally, physicians will focus on Proteomics applied to Clinical Microbiology, delving into qualitative and quantitative techniques for the separation and identification of relevant bacterial proteins. In addition, they will be updated in the use of bioinformatics tools for the analysis of proteomic and genomic data, applying innovative approaches in the identification of resistance profiles and in the design of personalized therapeutic strategies against Multidrug-Resistant Bacteria. 

Therefore, TECH has developed a complete, fully online and flexible university program that only requires an electronic device with an Internet connection to access all the teaching resources. In addition, it is based on the innovative Relearning methodology, which uses repetition of key concepts to ensure an effective and natural assimilation of information.

You will be equipped with the skills necessary to address the challenges associated with infections caused by Multidrug-Resistant Bacteria, including their clinical and molecular management. What are you waiting for to enroll?" 

This Postgraduate diploma in Postgraduate Diploma in Clinical and Molecular Management of Infections Caused by Multidrug-Resistant Bacteria contains the most complete and up-to-date scientific program on the market. The most important features include:  

• The development of practical cases presented by experts in Microbiology, Medicine and Parasitology
• The graphic, schematic and eminently practical contents with which it is conceived gather scientific and practical information on those disciplines that are indispensable for professional practice 
• Practical exercises where the self-assessment process can be carried out to improve learning
• Its special emphasis on innovative methodologies  
• Theoretical lessons, questions to the expert, debate forums on controversial topics, and individual reflection assignments 
• Content that is accessible from any fixed or portable device with an Internet connection

Bet on TECH! You will apply bioinformatics tools in Proteomics and Genomics, understanding antibiotic resistance at the molecular level and developing more precise and personalized therapeutic strategies”

The program’s teaching staff includes professionals from the field who contribute their work experience to this educational program, as well as renowned specialists from leading societies and prestigious universities. 

The multimedia content, developed with the latest educational technology, will provide the professional with situated and contextual learning, i.e., a simulated environment that will provide immersive education programmed to learn in real situations. 

This program is designed around Problem-Based Learning, whereby the professional must try to solve the different professional practice situations that arise during the course. For this purpose, students will be assisted by an innovative interactive video system created by renowned and experienced experts. 

You will examine the global situation of antibiotic resistance, according to current statistics and regional trends that impact the effectiveness of antimicrobial treatments. With all the TECH guarantees!"

You will be updated in specialized knowledge for the diagnosis and treatment of the most common Multidrug-Resistant Infections in the ICU, through an extensive library of multimedia resources"

This university program includes specialized modules that will analyze the causes and mechanisms of antibiotic resistance, from the lack of new antibiotics to the socioeconomic factors and health policies that influence its spread. In addition, advanced molecular and genomic diagnostic techniques will be addressed to identify resistant pathogens and determine their resistance profiles, therefore facilitating the application of targeted therapies and effective prevention strategies in critical clinical settings, such as Intensive Care Units. 

The content of this Postgraduate diploma will cover a wide range of topics crucial to the understanding and treatment of Multidrug-Resistant Bacteria, supported by the Relearning methodology”

Module 1. Multidrug-Resistant Bacteria in Human Pathology

1.1. Mechanisms of Acquired Resistance to Antibiotics

1.1.1. Acquisition of Resistance Genes
1.1.2. Mutations
1.1.3. Acquisition of Plasmids

1.2. Mechanisms of Intrinsic Resistance to Antibiotics

1.2.1. Blockage of Antibiotic Entry
1.2.2. Modification of the Antibiotic Target
1.2.3. Inactivation of the Antibiotic
1.2.4. Antibiotic Expulsion

1.3. Chronology and Evolution of Antibiotic Resistance

1.3.1. Discovery of Antibiotic Resistance
1.3.2. Plasmids
1.3.3. Evolution of Resistance
1.3.4. Current Trends in the Evolution of Antibiotic Resistance

1.4. Antibiotic Resistance in Human Pathology

1.4.1. Increased Mortality and Morbidity
1.4.2. Impact of Resistance on Public Health
1.4.3. Economic Cost Associated with Antibiotic Resistance

1.5. Multidrug-Resistant Human Pathogens

1.5.1. Acinetobacter Baumannii
1.5.2. Pseudomonas Aeruginosa
1.5.3. Enterobacteriaceae
1.5.4. Enterococcus Faecium
1.5.5. Staphylococcus Aureus
1.5.6. Helicobacter Pylori
1.5.7. Campylobacter Spp
1.5.8. Salmonellae
1.5.9. Neisseria Gonorrhoeae
1.5.10. Streptococcus Pneumoniae
1.5.11. Hemophilus Influenzae
1.5.12. Shigella Spp

1.6. Bacteria Highly Dangerous to Human Health: Update of the WHO List

1.6.1. Critical Priority Pathogens
1.6.2. High Priority Pathogens
1.6.3. Pathogens with Medium Priority

1.7. Analysis of the Causes of Antibiotic Resistance

1.7.1. Lack of New Antibiotics
1.7.2. Socioeconomic Factors and Health Policies
1.7.3. Poor Hygiene and Sanitation
1.7.4. Health Policies and Antibiotic Resistance
1.7.5. International Travel and Global Trade
1.7.6. Dispersal of High-Risk Clones
1.7.7. Emerging Pathogens with Resistance to Multiple Antibiotics

1.8. Antibiotic Use and Abuse in the Community

1.8.1. Prescription
1.8.2. Acquisition
1.8.3. Misuse of Antibiotics

1.9. Current Status of Antibiotic Resistance in the World

1.9.1. Global Statistics
1.9.2. Central and South America
1.9.3. Africa
1.9.4. Europe
1.9.5. North America
1.9.6. Asia and Oceania

1.10. Perspectives on Antibiotic Resistance

1.10.1. Strategies to Mitigate the Problem of Multidrug-Resistance
1.10.2. International Actions
1.10.3. Actions at the Global Level

Module 2. Management of Patients with Multidrug-Resistant Bacterial Infections in Intensive Care Units (ICU)

2.1. Colonization and Infection of Patients in ICUs

2.1.1. Types of ICUs
2.1.2. Epidemiology
2.1.3. Risk Factors Associated with Infection in ICUs

2.2. Impact of Nosocomial Infections in the Critically Ill Patient

2.2.1. Importance of Nosocomial Infections in ICUs
2.2.2. Risk Factors for Nosocomial Infections

2.2.2.1. Patient Factors
2.2.2.2. Factors of the ICU Environment
2.2.2.3. Factors Related to the Healthcare Personnel

2.2.3. Impact of Nosocomial Infections in Immunocompromised Patients
2.2.4. Impact on Length of Stay in the ICU

2.3. Pneumonia Associated with Mechanical Ventilation

2.3.1. Etiology
2.3.2. Diagnosis
2.3.3. Treatment

2.4. Urinary Tract Infections Associated with Catheters

2.4.1. Etiology
2.4.2. Diagnosis
2.4.3. Treatment

2.5. Primary Bacteremias and Catheter-Related Bacteremias

2.5.1. Etiology
2.5.2. Diagnosis
2.5.3. Treatment

2.6. Pseudomembranous Colitis

2.6.1. Etiology
2.6.2. Diagnosis
2.6.3. Treatment

2.7. Infections by Opportunistic Pathogens

2.7.1. Etiology
2.7.2. Diagnosis
2.7.3. Treatment

2.8. Appropriate Use of Antibiotics

2.8.1. Programs for the Optimization of Antibiotic use (PROA) in the ICU
2.8.2. Antibiotic Therapy Strategies for the Treatment of Gram-Negative Patients
2.8.3. Antibiotic Therapy Strategies for the Treatment of Gram-Positive Patients
2.8.4. Antibiotic Therapy Strategies for the Treatment of Co-Infections

2.9. Strategies for the Prevention of BMR Infections in the ICU

2.9.1. Hygiene Measures
2.9.2. Infection Control Measures
2.9.3. Protocols and Clinical Practice Guidelines
2.9.4. Education and Training of ICU Personnel
2.9.5. Participation of Patients and their Families

2.10. Infection Prevention Strategies in the ICU

2.10.1. Infection Prevention Strategies in the ICU According to the Focus

2.10.1.1. Pneumonia
2.10.1.2. Bacteremia
2.10.1.3. Urinary Infection

2.10.2. Evaluation and Quality Indicators in the Prevention of Infections
2.10.3. Evaluation and Continuous Improvement Tools
2.10.4. Successful Examples of Infection Prevention in ICUs

Module 3.  Proteomics in Clinical Microbiology

3.1. Proteomics in the Microbiology Laboratory

3.1.1. Evolution and Development of Proteomics
3.1.2. Importance in Microbiological Diagnosis
3.1.3. Proteomics of Multi-Resistant Bacteria

3.2. Qualitative Protein Separation Techniques

3.2.1. Two-Dimensional Electrophoresis (2DE)
3.2.2. DIGE Technology
3.2.3. Applications in Microbiology

3.3. Quantitative Protein Separation Techniques

3.3.1. Isotopic Labelling
3.3.2. High Performance Liquid Chromatography (HPLC)
3.3.3. Mass Spectrometry (MS)

3.3.3.1. MALDI-TOF Technologies in the Clinical Microbiology Laboratory

3.3.3.1.1. VITEK®MS System
3.3.3.1.2. MALDI Biotyper® System

3.4. MALDI-TOF Applications in Clinical Microbiology

3.4.1. Identification of Microorganisms
3.4.2. Characterization of Antibiotic Resistance
3.4.3. Bacterial Typing

3.5. Bioinformatics Tools for Proteomics

3.5.1. Proteomic Databases
3.5.2. Protein Sequence Analysis Tools
3.5.3. Visualization of Proteomic Data

3.6. Genomics in the Microbiology Laboratory

3.6.1. Evolution and Development of Genomics
3.6.2. Importance in Microbiological Diagnosis
3.6.3. Genomics of Multi-Resistant Bacteria

3.7. Types of Sequencing

3.7.1. Sequencing of Genes with Taxonomic Value
3.7.2. Sequencing of Genes of Taxonomic Value
3.7.3. Bulk Sequencing

3.8. Applications of Massive Sequencing in Clinical Microbiology

3.8.1. Whole Bacterial Genome Sequencing
3.8.2. Comparative Genomics
3.8.3. Epidemiological Surveillance
3.8.4. Microbial Diversity and Evolution Studies

3.9. Bioinformatics Tools for Genomics

3.9.1. Genomic Databases
3.9.2. Sequence Analysis Tools
3.9.3. Visualization of Genomic Data

3.10. Future of Genomics and Proteomics in the Clinical Laboratory

3.10.1. Recent and Future Developments in Genomics and Proteomics
3.10.2. Development of New Therapeutic Strategies
3.10.3. Technical and Bioinformatics Challenges
3.10.4. Ethical and Regulatory Implications

TECH's comprehensive and specialized approach will prepare you to meet the challenges related to Multidrug-Resistant Bacteria, promoting better clinical outcomes and efficient management of antimicrobial resistance”